Up to half of all people living with Alzheimer’s Disease in Ireland remain undiagnosed. Now, a new blood test may have the potential to transform patient care, allowing for better diagnosis, earlier interventions and more targeted treatments. Researchers at Trinity College Dublin, the Tallaght Institute of Memory and Cognition and St James’s Hospital, Dublin are exploring… Continue reading Innovative blood test shows potential to replace spinal tap for Alzheimer’s diagnosis
Category: Immunology
Infants with cystic fibrosis show stunted gut microbiome development
Findings from a new Dartmouth-led study, published in the journal mBio, highlight key differences in the gut microbiome (communities of bacteria) of infants with cystic fibrosis (CF) compared to that of healthy infants, and how these alterations may adversely affect their health. CF is a multi-organ genetic disease that causes sticky mucus to build up in the lungs… Continue reading Infants with cystic fibrosis show stunted gut microbiome development
Linking vaccine adjuvant mechanisms of action to function
Science Immunology, Volume 10, Issue 104, February 2025.
TRAF3 is critical for initial T follicular helper cell specification via coordination of the IL-6R/IL-2R–BCL6 signaling nexus
Science Immunology, Volume 10, Issue 104, February 2025.
Enzyme found in lymphatic cells enhances immune activity against tumors
When a tumor develops, it creates a structure around itself called the tumor stroma, within which blood and lymphatic vessels ensure nutritional and respiratory biological exchanges. Lymphangiogenesis, i.e. the development of lymphatic vessels, is generally associated with a poor prognosis, as it favours the spread of metastases to other organs. By studying the cells that… Continue reading Enzyme found in lymphatic cells enhances immune activity against tumors
Study explains why tecovirimat fails against some mpox strains
A virus originally found in animals, mpox – which causes the disease of the same name – is now circulating in humans. Since 2022, it has been the cause of major epidemics spreading outside endemic areas in Central and West Africa. Two hundred and fifteen cases of mpox infection were reported to Santé publique France… Continue reading Study explains why tecovirimat fails against some mpox strains
Immunocompromised individuals need regular boosters for Covid-19 protection
Vaccinations alone may not be enough to protect people with compromised immune systems from infection, even if the vaccine has generated the production of antibodies, new research from the University of Cambridge has shown. The findings, published today in Science Advances, suggest that such individuals will need regular vaccine boosters to protect them and reduce… Continue reading Immunocompromised individuals need regular boosters for Covid-19 protection